Contactul. Lwowska 1, 87-100 Toruń
tel.: +48 56 611-25-05
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zdjęcie nagłówkowe



  1. Annamaria Antona, Marco Varalda , Konkonika Roy, Francesco Favero, Eleonora Mazzucco,Miriam Zuccalà, Giovanni Leo, Giulia Soggia, Valentina Bettio, Martina Tosi, Miriam Gaggianesi, Beatrice Riva, Simone Reano, Armando Genazzani, Marcello Manfredi, Giorgio Stassi, Davide Corà, Sandra D’Alfonso, Daniela Capello. Dissecting the Mechanism of Action of Spiperone—A Candidate for Drug Repurposing for Colorectal Cancer. Cancers  14, 776, 2022.  (IF=6,639; MNiSW=140 pkt.; Q1)
  2. Aleksander Zwierz, Krystyna Masna, Krzysztof Domagalski, Paweł Burduk. The Long-Term Effects of 12-Week Intranasal Steroid Therapy on Adenoid Size, Its Mucus Coverage and Otitis Media with Effusion: A Cohort Study in Preschool Children. Journal of Clinical Medicine 11(3), 507, 2022. (IF=4,242; MNiSW=140 pkt.; Q1)
  3. Agata Kućko , Aleksandra Bogumiła Florkiewicz , Magdalena Wolska, Jakub Miętki , Małgorzata Kapusta , Krzysztof Domagalski and Emilia Wilmowicz. Jasmonate-Dependent Response of the Flower Abscission Zone Cells to Drought in Yellow Lupine. Plants 11(4), 527, 2022. (IF=3,935; MNiSW=70 pkt.; Q1)


  1. Ewelina Ziemlińska, Justyna Sobocińska, Anna Świątkowska, Aneta Hromada-Judycka, Gabriela Traczyk, Agata Malinowska, Bianka Świderska, Anna Mietelska-Porowska, Anna Ciesielska and Katarzyna Kwiatkowska. Palm Oil-Rich Diet Affects Murine Liver Proteome and S-Palmitoylome. International Journal of Molecular Sciences 22(23), 13094, 2021. (IF=5,923; MNiSW=140 pkt.; Q1)
  2. Krystyna Masna, Aleksander Zwierz, Krzysztof Domagalski, Paweł Burduk. The Impact of the Thermal Seasons on Adenoid Size, Its Mucus Coverage and Otitis Media with Effusion: A Cohort Study. Journal of Clinical Medicine 10(23), 5603, 2021. (IF=4,241; MNiSW=140 pkt.; Q1)
  3. Wojciech J. Bilinski, Lukasz Szternel, Joanna Siodmiak, Przemyslaw T. Paradowski, Krzysztof Domagalski and Grazyna Sypniewska. Low Serum 25-hydroxyvitamin D Level Does Not Adversely Affect Bone Turnover in Prepubertal Children. Nutrients 13(10), 3324, 2021. (IF=5,719; MNiSW=140 pkt.; Q1)
  4. Wojciech J. Bilinski, Lukasz Szternel, Joanna Siodmiak, Magdalena Krintus, Przemyslaw T. Paradowski, Krzysztof Domagalski, Grazyna Sypniewska. Effect of fasting hyperglycemia and insulin resistance on bone turnover markers in children aged 9-11 years. Journal of  Diabetes and Its Complications 35(10), 108000, 2021. (IF=2,852, MNiSW=100 pkt.)
  5. Henryk M. Kozłowski, Małgorzata Pawlikowska, Justyna Sobocińska, Tomasz Jędrzejewski, Artur Dzialuk and Sylwia Wrotek. Distinct Modulatory Effects of Fever‐Range Hyperthermia
    on the Response of Breast Cancer Cells and Macrophages to Mistletoe (Viscum album L.) Extract. Pharmaceuticals 14(6), 551, 2021.
  6. Małgorzata PawlikowskaTomasz Jędrzejewski, Andrzej Slominski, Anna Brożyna and Sylwia Wrotek. Pigmentation levels affect melanoma responses to Coriolus versicolor extract and play a crucial role in melanoma-mononuclear cell crosstalk. International Journal of Molecular Sciences 22 (11), 5735, 2021.
  7. Skorupa Monika, Szczepanek Joanna, Mazur Justyna, Domagalski Krzysztof, Tretyn Andrzej, Tyburski Jarosław. Salt stress and salt shock differently affect DNA methylation in salt-responsive genes in sugar beet and its wild, halophytic ancestor. PLoS One 16(5), e0251675, 2021.
  8. Michalina Ehlert, Aleksandra Radtke, Katarzyna Roszek, Tomasz Jędrzejewski, and Piotr Piszczek. Assessment of Titanate Nanolayers in Terms of Their Physicochemical and Biological Properties. Materials 14(4), 806, 2021.
  9. Oskar Wiśniewski, Wiesław Kozak, Maciej Wiśniewski. The ground-level ozone concentration is inversely correlated with the number of COVID-19 cases in Warsaw, Poland. Air Qual Atmos Health Apr 8: 1-5, 2021.
  10. Marzena Fandzloch, Tomasz Jędrzejewski, Liliana Dobrzańska, Ginés M. Esteban-Parra, Joanna Wiśniewska, Agata Paneth, Piotr Paneth and Jerzy Sitkowski. New organometallic ruthenium(II) complexes with purine analogs – a wide perspective on their biological application. Dalton Transactions 50, 5557-5573, 2021.
  11. Magdalena Wypij, Tomasz Jędrzejewski, Joanna Trzcińska-Wencel, Maciej Ostrowski, Mahendra Rai and Patrycja Golinska. Green synthesized silver nanoparticles: antibacterial and anticancer acitivities, biocompatibility, and analyses of surface-attached proteins. Frontiers in Microbiology 12:632505, 2021.


  1. Sylwia Wrotek, Edmund K. LeGrand, Artur Dzialuk, Joe Alcock. Let fever do its job: the meaning of fever in the pandemic era. Evolution, Medicine, and Public Health, eoaa044, 1-29, 2020.
  2. Tomasz Jędrzejewski, Justyna Sobocińska, Małgorzata Pawlikowska, Artur Dzialuk, Sylwia Wrotek. Extract from the Coriolus versicolor Fungus as an Anti-Inflammatory Agent with Cytotoxic Properties against Endothelial Cells and Breast Cancer Cells. International Journal of Molecular Sciences 21(23), 9063, 2020.
  3. Małgorzata Pawlikowska, Tomasz Jędrzejewski, Anna A. Brożyna, Sylwia Wrotek. Protein-bound polysaccharides from Coriolus versicolor induce RIPK1/RIPK3/MLKL-mediated necroptosis in ER-positive breast cancer and amelanotic melanoma cells. Cellular Physiology and Biochemistry 54, 591-604, 2020.
  4. Tomasz Jędrzejewski, Małgorzata Pawlikowska, Justyna Sobocińska, Sylwia Wrotek. Protein-Bound Polysaccharides from Coriolus versicolor Fungus Disrupt the Crosstalk between Breast Cancer Cells and Macrophages through Inhibition of Angiogenic Cytokines Production and Shifting Tumour-Associated Macrophages from the M2 to M1 Subtype. Cellular Physiology and Biochemistry 54, 615-628, 2020.
  5. Beata Smok, Krzysztof Domagalski, Małgorzata Pawłowska. Diagnostic and Prognostic Value of IL-6 and sTREM-1 in SIRS and Sepsis in Children. Mediators of Inflammation Volume 2020, Article ID 8201585, 8 pages, 2020.
  6. Sylwia Wrotek, Justyna Sobocińska, Henryk M. Kozłowski, Małgorzata Pawlikowska, Tomasz Jędrzejewski, Artur Dzialuk. New insights into the role of glutathione in the mechanism of fever. International Journal of Molecular Science 21(4), 1393, 2020.
  7. Sylwia Wrotek, Anna Nowakowska, Michał Caputa, Wiesław Kozak. Unbalanced thermoregulation in experimental autoimmune encephalitis induced in Lewis rats. Journal of Thermal Biology 89, 102529, 2020.
  8. Małgorzata Pawlikowska, Jakub Piotrowski, Tomasz Jędrzejewski, Wiesław Kozak, Andrzej T. Slominski, Anna A. Brożyna. Coriolus versicolor‐derived protein‐bound polysaccharides trigger the caspase‐independent cell death pathway in amelanotic but not melanotic melanoma cells. Phytotherapy Research 34(1), 173-183, 2020.
  9. Piotr Piszczek, Aleksandra Radtke, Michalina Ehlert, Tomasz Jędrzejewski, Alicja Sznarkowska, Beata Sadowska, Michał Bartmański, Yaşar Kemal Erdoğan, Batur Ercan, Waldemar Jedrzejczyk. Comprehensive evaluation of biological properties of surface modified titanium alloy implants. Journal of Clinical Medicine 9(2), 342, 2020.
  10. Marzena Fandzloch, Liliana Dobrzańska, Tomasz Jędrzejewski, Julia Jezierska, Joanna Wiśniewska, Iwona Łakomska. Synthesis, structure and biological evaluation of ruthenium(III) complexes of triazolopyrimidines with anticancer properties. Journal of Biological Inorganic Chemistry 25, 109-124, 2020.
  11. Michalina Ehlert, Aleksandra Radtke, Tomasz Jędrzejewski , Katarzyna Roszek, Michał Bartmański, Piotr Piszczek. In vitro studies on nanoporous, nanotubular and nanosponge-like titania coatings, with the use of adipose-derived stem cells. Materials 13(7), 1574, 2020.
  12. Marzena Fandzloch, Adam Wiktor Augustyniak, Liliana Dobrzanska, Tomasz Jędrzejewski, Jerzy Sitkowski, Magdalena Wypij, Patrycja Golinska. First dinuclear rhodium (II) complexes with triazolopyrimidines and the prospect of their potential biological use. Journal of Inorganic Biochemistry 210, 111072, 2020.
  13. Magdalena Wypij, Tomasz Jędrzejewski, Maciej Ostrowski, Joanna Trzcińska, Mahendra Rai, Patrycja Golińska. Biogenic Silver Nanaparticles: Assessment of Their Cytotoxicity, Genotoxicity and Study of Capping Proteins. Molecules 25(13), 3022, 2020.


  1. Aleksandra Radtke, Michalina Ehlert, Tomasz Jędrzejewski, Beata Sadowska, Marzena Więckowska-Szakiel, Jani Holopainen, Mikko Ritala, Markku Leskelä, Michał Bartmański, Marek Szkodo, Piotr Piszczek. Titania nanotubes/hydroxyapatite nanocomposites produced with the use of the atomic layer deposition technique: estimation of bioactivity and nanomechanical properties. Nanomaterials 9(1), 123, 2019.
  2. Aleksandra Radtke, Michalina Ehlert, Tomasz Jędrzejewski, Michał Bartmański. The Morphology, Structure, Mechanical Properties and Biocompatibility of Nanotubular Titania Coatings before and after Autoclaving Process. Journal of Clinical Medicine 8(2), 272, 2019.
  3. Aleksandra Radtke, Marlena Grodzicka, Michalina Ehlert, Tomasz Jędrzejewski, Magdalena Wypij, Patrycja Golińska. “To be Microbiocidal and Not to be Cytotoxic at the Same Time…” – Silver nanoparticles and Their Main Role on the Surface of Titanium Alloy Implants. Journal of Clinical Medicine 8(3), 334, 2019.
  4. Tomasz Jędrzejewski, Jakub Piotrowski, Małgorzata Pawlikowska, Sylwia Wrotek, Wieslaw Kozak. Extract from Coriolus versicolor fungus partially prevents endotoxin tolerance development by maintaining febrile response and increasing IL-6 generation. Journal of Thermal Biology 83, 69-79, 2019.
  5. Jakub Piotrowski, Tomasz Jędrzejewski, Małgorzata Pawlikowska, Sylwia Wrotek Wieslaw Kozak. High mobility group box 1 protein released in the course of aseptic necrosis of tissues sensitizes rats to pyrogenic effects of lipopolysaccharide. Journal of Thermal Biology 84, 36-44, 2019.


  1. Aleksandra Radtke, Monika Bal, Tomasz Jędrzejewski. Novel titania nanocoatings produced by the anodic oxidation with the use of the cyclically changing potential; their photocatalytic activity and biocompatibility. Nanomaterials 8(9), 712, 2018.
  2. Wieslaw Kozak, Tomasz Jedrzejewski, Malgorzata Pawlikowska, Jakub Piotrowski, Sylwia Wrotek. Towards antitumor immunity and acute infectious fever: gamma/delta T cells hypothesis. Quarterly Review of Biology 93(3), 187-205, 2018.
  3. Sylwia Wrotek, Łukasz Brycht, Weronika Wrotek, Wiesław Kozak. Fever as a factor contributing to long-term survival in a patient with metastatic melanoma: a case report. Complementary Therapies in Medicine 38, 7-10, 2018.
  4. Joanna Wyszkowska, Tomasz Jędrzejewski, Jakub Piotrowski, Anna Wojciechowska, Maria Stankiewicz, Wieslaw Kozak. Evaluation of the influence of in vivo exposure to extremely low-frequency magnetic fields on the plasma levels of pro-inflammatory cytokines in rats. International Journal of Radiation Biology 94(10), 909-917, 2018.


  1. Piotr Piszczek, Żaneta Lewandowska, Aleksandra Radtke, Tomasz Jędrzejewski, Wiesław Kozak, Beata Sadowska, Magdalena Szubka, Ewa Talik, Fabrizio Fiori. Biocompatibility of Titania Nanotube Coatings Enriched with Silver Nanograins by Chemical Vapor Deposition. Nanomaterials 7(9), 274, 2017.
  2. Jakub Piotrowski, Tomasz Jędrzejewski, Małgorzata Pawlikowska, Agata Joanna Pacuła, Jacek Ścianowski, Wiesław Kozak. The weakening effect of soluble epoxide hydrolase inhibitor AUDA on febrile response to lipopolysaccharide and turpentine in rat. Journal of Physiology and Biochemistry 73: 551-560, 2017.
  3. Aleksandra Radtke, Tomasz Jędrzejewski, Wiesław Kozak, Beata Sadowska, Marzena Więckowska-Szakiel, Ewa Talik, Maarit Mäkelä, Markku Leskelä, Piotr Piszczek. Optimization of the Silver Nanoparticles PEALD Process on the Surface of 1-D Titania Coatings. Nanomaterials 7(7), 193, 2017.
  4. Aleksandra Radtke, Adrian Topolski, Tomasz Jędrzejewski, Wiesław Kozak, Beata Sadowska, Marzena Więckowska-Szakiel, Magdalena Szubka, Ewa Talik, Lars Pleth Nielsen, Piotr Piszczek. The bioactivity and photocatalytic properties of titania nanotube coatings produced with the use of the low potential anodization of Ti6Al4V alloy surface. Nanomaterials 7(8), 197, 2017.
  5. Jakub Piotrowski, Tomasz Jędrzejewski, Małgorzata Pawlikowska, Wiesław Kozak. Znaczenie gorączki i endogennej antypirezy. Perspektywa wykorzystania inhibitorów rozpuszczalnej hydrolazy epoksydowej w farmakologii przeciwgorączkowej. Kosmos 66 (2): 327-335, 2017.
  6. Aleksandra Radtke, Adrian Topolski, Tomasz Jędrzejewski, Wiesław Kozak, Beata Sadowska, Marzena Więckowska-Szakiel, Piotr Piszczek. Bioactivity Studies on Titania Coatings and the Estimation of Their Usefulness in the Modification of Implants Surface. Nanomaterials 7(4), 90, 2017.
  7. Sylwia Wrotek, Krzysztof Domagalski, Tomasz Jędrzejewski, Eliza Dec, Wiesław Kozak. Buthionine sulfoximine, a glutathione depletor, attenuates endotoxic fever and reduces IL-1b and IL-6 level in rats. Cytokine 90: 31-37, 2017.


  1. Małgorzata Pawlikowska, Tomasz Jedrzejewski, Jakub Piotrowski, Wiesław Kozak. Fever-range hyperthermia inhibits cells immune response to protein-bound polysaccharides derived from Coriolus versicolor extract. Molecular Immunology 80: 50-57, 2016.
  2. Tomasz Jędrzejewski, Małgorzata Pawlikowska, Jakub Piotrowski, Wiesław Kozak. Protein-bound polysaccharides from Coriolus versicolor attenuate LPS-induced synthesis of pro-inflammatory cytokines and stimulate PBMCs proliferation. Immunology Letters 178: 140-147, 2016.
  3. Sylwia Wrotek, Tomasz Jędrzejewski, Jakub Piotrowski, Wiesław Kozak. N-acetyl-L-cysteine exacerbates generation of IL-10 in cells stimulated with endotoxin in vitro and produces antipyresis via IL-10 dependent pathway in vivo. Immunology Letters 177: 1-5, 2016.
  4. Małgorzata Kowalczewska, Jakub Piotrowski, Tomasz Jędrzejewski, Wiesław Kozak. Polysaccharide peptides from Coriolus versicolor exert differential immunomodulatory effects on blood lymphocytes and breast cancer cell line MCF-7 in vitro. Immunology Letters 174: 37-44, 2016.
  5. Sylwia Wrotek, Tomasz Jędrzejewski, Anna Nowakowska, Wiesław Kozak. LPS alters pattern of sickness behavior but does not affect glutathione level in aged male rats. Biogerontology 17: 715-723, 2016.