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zdjęcie nagłówkowe



  1. Aleksander Zwierz, Krzysztof Domagalski, Krystyna Masna, Paweł Burduk. Maximal medical treatment of adenoid hypertrophy: a prospective study of preschool children. European Archives of Oto-Rhino-Laryngology 2024 (IF=2,6; MNiSW=70 pkt.; Q2)
  2. Barbara Kubiak, Tadeusz Muzioł, Grzegorz Wrzeszcz, Aleksandra Radtke, Patrycja Golińska, Tomasz Jędrzejewski, Sylwia Wrotek, Piotr Piszczek. Structural Characterization and Bioactivity of a Titanium(IV) ‐Oxo Complex Stabilized by Mandelate Ligands. Molecules 29(8), 1736, 2024. (IF=4,6; MNiSW=140 pkt.; Q2)
  3. Jakub Piotrowski, Tomasz Jędrzejewski. High mobility group box protein 1 sensitizes mononuclear cells for further contact with lipopolysaccharide. Central European Journal of Immunology 49(1), 1-8, 2024. (IF=1,3; MNiSW=70 pkt.; Q4)


  1. Justyna Moppert, Krzysztof Domagalski, Małgorzata Pawłowska. Significance of expression of selected miRNAs in the diagnosis of hepatological complications of Epstein-Barr virus infection in children. Clinical and Experimental Hepatology 9(3), 279-285, 2023. (IF=1,5; MEiN=200 pkt.)
  2. Justyna Moppert, Krzysztof Domagalski, Sylwia Wrotek and Małgorzata Pawłowska. Are Selected Cytokines and Epstein–Barr Virus DNA Load Predictors of Hepatological Complications of Epstein–Barr Virus Infection in Children? Journal of Clinical Medicine 12(19), 6158, 2023. (IF=3,9; MEiN=140 pkt.; Q2)
  3. Henryk Mikołaj Kozłowski, Justyna Sobocińska, Tomasz Jędrzejewski, Bartosz Maciejewski, Artur Dzialuk, Sylwia Wrotek. Fever-Range Hyperthermia Promotes Macrophage Polarization towards Regulatory Phenotype M2b. International Journal of Molecular Sciences 24(24), 17574, 2023. (IF=5,6; MEiN=140 pkt.; Q1)
  4. Konkonika Roy, Henryk Mikołaj Kozłowski, Tomasz Jędrzejewski, Justyna Sobocińska, Bartosz Maciejewski, Artur Dzialuk, Sylwia Wrotek. Endotoxin Tolerance Creates Favourable Conditions for Cancer Development. Cancers 15(20), 5113, 2023. (IF=5,2; MEiN=200 pkt.; Q2)
  5. Aleksander Zwierz, Krystyna Masna, Krzysztof Domagalski, Paweł K. Burduk. 150th anniversary of global adenoid investigations: Unanswered questions and unsolved problems. Frontiers in Pediatrics 11, 1179218, 2023. (IF=2,6; MEiN=70 pkt.; Q2)
  6. Aleksander Zwierz, Krzysztof Domagalski, Krystyna Masna, Paweł Walentowicz, Paweł Burduk. Impact of Breastfeeding Duration on Adenoid Hypertrophy, Snoring and Acute Otitis Media: A Case-Control Study in Preschool Children. Journal of Clinical Medicine 12(24), 7683, 2023. (IF=3,9; MEiN=140 pkt.; Q2)
  7. Gabriela Gąsior, Marlena Grodzicka, Tomasz Jędrzejewski, Marek Wiśniewski and Aleksandra Radtke. Comparative Study of Porous Iron Foams for Biodegradable Implants: Structural Analysis and In Vitro Assessment. Journal of Functional Biomaterials 14(6), 293, 2023. (IF=4,8; MEiN=100 pkt.; Q2)
  8. Henryk Mikołaj Kozłowski, Justyna Sobocińska, Tomasz Jędrzejewski, Bartosz Maciejewski, Artur Dzialuk, Sylwia Wrotek. Fever-range whole body hyperthermia leads to changes in immune-related genes and miRNA machinery in Wistar rats. International Journal of Hyperthermia 40(1), 2216899, 2023. (IF=3,1; MEiN=100 pkt.; Q2)
  9. Tomasz Jędrzejewski, Małgorzata Pawlikowska, Justyna Sobocińska, Sylwia Wrotek. COVID-19 and cancer – the potential of Coriolus versicolor mushroom to combat global health challenges. International Journal of Molecular Sciences 24(5), 4864, 2023. (IF=5,6; MEiN=140 pkt.; Q1)
  10. Aleksander Zwierz, Krzysztof Domagalski, Krystyna Masna and Paweł Burduk. Siblings’ Risk of Adenoid Hypertrophy: A Cohort Study in Children. International Journal of Environmental Research and Public Health 20(4), 2910, 2023. (MEiN=20 pkt.)
  11. Julia Śmigiel, Piotr Piszczek, Grzegorz Wrzeszcz, Tomasz Jędrzejewski, Patrycja Golińska and Aleksandra Radtke. The Composites of PCL and Tetranuclear Titanium(IV)-Oxo Complex with Acetylsalicylate Ligands – Assessment of Their Biocompatibilty and Antimicrobial Activity with the Correlation to EPR Spectroscopy. Materials 16(1), 297, 2023. (IF=3,4; MEiN=140 pkt.; Q3)
  12. Moppert Justyna, Pawłowska Małgorzata, Domagalski Krzysztof, Szwed-Kowalska Aleksandra. The concentration of IL-6, TNF-α, s-ICAM-1, and EBV DNA load – predictive factors of hepatological complications in children with infectious mononucleosis: a pilot study, Pediatria Polska 98(1), 1-9, 2023. (MEiN=100 pkt.)


  1. Aleksander Zwierz, Krzysztof Domagalski, Krystyna Masna, Paweł Burduk. Effectiveness of Evaluation of Adenoid Hypertrophy in Children by Flexible Nasopharyngoscopy Examination (FNE), Proposed Schema of Frequency of Examination: Cohort Study. Diagnostics 12(7), 1734, 2022. (IF=3,992; MEiN=70 pkt.; Q2)
  2. Michalina Ehlert, Aleksandra Radtke, Natalia Forbot, Tomasz Jędrzejewski, Katarzyna Roszek, Patrycja Golińska, Grzegorz Trykowski and Piotr Piszczek. TiO2/HA and Titanate/HA Double-Layer Coatings on Ti6Al4V Surface and Their Influence on In Vitro Cell Growth and Osteogenic Potential. Journal of Functional Biomaterials 13(4), 271, 2022. (IF=4,901; MEiN=100 pkt.; Q2)
  3. Tomasz Jędrzejewski, Justyna Sobocińska, Małgorzata Pawlikowska, Artur Dzialuk, Sylwia Wrotek. Dual Effect of the Extract from the Fungus Coriolus Versicolor on Lipopolysaccharide-Induced Cytokine Production in RAW 264.7 Macrophages Depending on the Lipopolysaccharide Concentration. Journal of Inflammation Research 15, 3599-3611, 2022. (IF=4,631; MEiN=140 pkt.; Q2)
  4. Marzena Fandzloch, Tomasz Jędrzejewski, Joanna Wiśniewska, Jerzy Sitkowski, Liliana Dobrzańska, Anna A. Brożyna and Sylwia Wrotek. Sawhorse-type ruthenium complexes with triazolopyrimidine ligands – what do they represent in terms of cytotoxic and CORM compounds? Dalton Transactions 51(22), 8804-8820, 2022. (IF=4,569; MEiN=140 pkt.; Q1)
  5. Annamaria Antona, Marco Varalda , Konkonika Roy, Francesco Favero, Eleonora Mazzucco,Miriam Zuccalà, Giovanni Leo, Giulia Soggia, Valentina Bettio, Martina Tosi, Miriam Gaggianesi, Beatrice Riva, Simone Reano, Armando Genazzani, Marcello Manfredi, Giorgio Stassi, Davide Corà, Sandra D’Alfonso, Daniela Capello. Dissecting the Mechanism of Action of Spiperone—A Candidate for Drug Repurposing for Colorectal Cancer. Cancers  14, 776, 2022.  (IF=6,575; MEiN=140 pkt.; Q1)
  6. Aleksander Zwierz, Krystyna Masna, Krzysztof Domagalski, Paweł Burduk. The Long-Term Effects of 12-Week Intranasal Steroid Therapy on Adenoid Size, Its Mucus Coverage and Otitis Media with Effusion: A Cohort Study in Preschool Children. Journal of Clinical Medicine 11(3), 507, 2022. (IF=4,964; MEiN=140 pkt.; Q2)
  7. Agata Kućko , Aleksandra Bogumiła Florkiewicz , Magdalena Wolska, Jakub Miętki , Małgorzata Kapusta , Krzysztof Domagalski and Emilia Wilmowicz. Jasmonate-Dependent Response of the Flower Abscission Zone Cells to Drought in Yellow Lupine. Plants 11(4), 527, 2022. (IF=4,658; MEiN=70 pkt.; Q1)


  1. Ewelina Ziemlińska, Justyna Sobocińska, Anna Świątkowska, Aneta Hromada-Judycka, Gabriela Traczyk, Agata Malinowska, Bianka Świderska, Anna Mietelska-Porowska, Anna Ciesielska and Katarzyna Kwiatkowska. Palm Oil-Rich Diet Affects Murine Liver Proteome and S-Palmitoylome. International Journal of Molecular Sciences 22(23), 13094, 2021. (IF=5,923; MEiN=140 pkt.; Q1)
  2. Krystyna Masna, Aleksander Zwierz, Krzysztof Domagalski, Paweł Burduk. The Impact of the Thermal Seasons on Adenoid Size, Its Mucus Coverage and Otitis Media with Effusion: A Cohort Study. Journal of Clinical Medicine 10(23), 5603, 2021. (IF=4,241; MEiN=140 pkt.; Q1)
  3. Wojciech J. Bilinski, Lukasz Szternel, Joanna Siodmiak, Przemyslaw T. Paradowski, Krzysztof Domagalski and Grazyna Sypniewska. Low Serum 25-hydroxyvitamin D Level Does Not Adversely Affect Bone Turnover in Prepubertal Children. Nutrients 13(10), 3324, 2021. (IF=5,719; MEiN=140 pkt.; Q1)
  4. Wojciech J. Bilinski, Lukasz Szternel, Joanna Siodmiak, Magdalena Krintus, Przemyslaw T. Paradowski, Krzysztof Domagalski, Grazyna Sypniewska. Effect of fasting hyperglycemia and insulin resistance on bone turnover markers in children aged 9-11 years. Journal of  Diabetes and Its Complications 35(10), 108000, 2021. (IF=2,852, MEiN=100 pkt.)
  5. Henryk M. Kozłowski, Małgorzata Pawlikowska, Justyna Sobocińska, Tomasz Jędrzejewski, Artur Dzialuk and Sylwia Wrotek. Distinct Modulatory Effects of Fever‐Range Hyperthermia on the Response of Breast Cancer Cells and Macrophages to Mistletoe (Viscum album L.) Extract. Pharmaceuticals 14(6), 551, 2021. (IF=5,863; MEiN=100 pkt.; Q1)
  6. Małgorzata PawlikowskaTomasz Jędrzejewski, Andrzej Slominski, Anna Brożyna and Sylwia Wrotek. Pigmentation levels affect melanoma responses to Coriolus versicolor extract and play a crucial role in melanoma-mononuclear cell crosstalk. International Journal of Molecular Sciences 22(11), 5735, 2021. (IF=5,923; MEiN=140 pkt.; Q1)
  7. Skorupa Monika, Szczepanek Joanna, Mazur Justyna, Domagalski Krzysztof, Tretyn Andrzej, Tyburski Jarosław. Salt stress and salt shock differently affect DNA methylation in salt-responsive genes in sugar beet and its wild, halophytic ancestor. PLoS One 16(5), e0251675, 2021. (IF:=3,24; MEiN=100 pkt.; Q2)
  8. Michalina Ehlert, Aleksandra Radtke, Katarzyna Roszek, Tomasz Jędrzejewski, and Piotr Piszczek. Assessment of Titanate Nanolayers in Terms of Their Physicochemical and Biological Properties. Materials 14(4), 806, 2021. (IF=3,623; MEiN=140 pkt.; Q2)
  9. Oskar Wiśniewski, Wiesław Kozak, Maciej Wiśniewski. The ground-level ozone concentration is inversely correlated with the number of COVID-19 cases in Warsaw, Poland. Air Qual Atmos Health Apr 8: 1-5, 2021. (IF=3,763; MEiN=70 pkt.; Q2)
  10. Marzena Fandzloch, Tomasz Jędrzejewski, Liliana Dobrzańska, Ginés M. Esteban-Parra, Joanna Wiśniewska, Agata Paneth, Piotr Paneth and Jerzy Sitkowski. New organometallic ruthenium(II) complexes with purine analogs – a wide perspective on their biological application. Dalton Transactions 50, 5557-5573, 2021. (IF=4,39; MEiN=140 pkt.; Q1)
  11. Magdalena Wypij, Tomasz Jędrzejewski, Joanna Trzcińska-Wencel, Maciej Ostrowski, Mahendra Rai and Patrycja Golinska. Green synthesized silver nanoparticles: antibacterial and anticancer acitivities, biocompatibility, and analyses of surface-attached proteins. Frontiers in Microbiology 12:632505, 2021. (IF=5,64; MEiN=100 pkt.; Q1)
  12. Sylwia Wrotek, Edmund K. LeGrand, Artur Dzialuk, Joe Alcock. Let fever do its job: the meaning of fever in the pandemic era. Evolution, Medicine, and Public Health 9(1), 26-35, 2021. (IF=5,425; MEiN=70 pkt.; Q1)


  1. Tomasz Jędrzejewski, Justyna Sobocińska, Małgorzata Pawlikowska, Artur Dzialuk, Sylwia Wrotek. Extract from the Coriolus versicolor Fungus as an Anti-Inflammatory Agent with Cytotoxic Properties against Endothelial Cells and Breast Cancer Cells. International Journal of Molecular Sciences 21(23), 9063, 2020. (IF=5,923; MNiSW=140; Q1)
  2. Małgorzata Pawlikowska, Tomasz Jędrzejewski, Anna A. Brożyna, Sylwia Wrotek. Protein-bound polysaccharides from Coriolus versicolor induce RIPK1/RIPK3/MLKL-mediated necroptosis in ER-positive breast cancer and amelanotic melanoma cells. Cellular Physiology and Biochemistry 54, 591-604, 2020. (IF=5,5; MNiSW=140 pkt.; Q1)
  3. Tomasz Jędrzejewski, Małgorzata Pawlikowska, Justyna Sobocińska, Sylwia Wrotek. Protein-Bound Polysaccharides from Coriolus versicolor Fungus Disrupt the Crosstalk between Breast Cancer Cells and Macrophages through Inhibition of Angiogenic Cytokines Production and Shifting Tumour-Associated Macrophages from the M2 to M1 Subtype. Cellular Physiology and Biochemistry 54, 615-628, 2020. (IF=5,5; MNiSW=140 pkt.; Q1)
  4. Beata Smok, Krzysztof Domagalski, Małgorzata Pawłowska. Diagnostic and Prognostic Value of IL-6 and sTREM-1 in SIRS and Sepsis in Children. Mediators of Inflammation Volume 2020, Article ID 8201585, 8 pages, 2020. (IF=4,711; MNiSW=100 pkt.; Q2)
  5. Sylwia Wrotek, Justyna Sobocińska, Henryk M. Kozłowski, Małgorzata Pawlikowska, Tomasz Jędrzejewski, Artur Dzialuk. New insights into the role of glutathione in the mechanism of fever. International Journal of Molecular Science 21(4), 1393, 2020. (IF=5,923; MNiSW=140; Q1)
  6. Sylwia Wrotek, Anna Nowakowska, Michał Caputa, Wiesław Kozak. Unbalanced thermoregulation in experimental autoimmune encephalitis induced in Lewis rats. Journal of Thermal Biology 89, 102529, 2020. (IF=2,902; MNiSW=70 pkt.; Q2)
  7. Małgorzata Pawlikowska, Jakub Piotrowski, Tomasz Jędrzejewski, Wiesław Kozak, Andrzej T. Slominski, Anna A. Brożyna. Coriolus versicolor‐derived protein‐bound polysaccharides trigger the caspase‐independent cell death pathway in amelanotic but not melanotic melanoma cells. Phytotherapy Research 34(1), 173-183, 2020. (IF=5,878; MNiSW=100 pkt.; Q1)
  8. Piotr Piszczek, Aleksandra Radtke, Michalina Ehlert, Tomasz Jędrzejewski, Alicja Sznarkowska, Beata Sadowska, Michał Bartmański, Yaşar Kemal Erdoğan, Batur Ercan, Waldemar Jedrzejczyk. Comprehensive evaluation of biological properties of surface modified titanium alloy implants. Journal of Clinical Medicine 9(2), 342, 2020. (IF=4,241; MNiSW=140 pkt.; Q1)
  9. Marzena Fandzloch, Liliana Dobrzańska, Tomasz Jędrzejewski, Julia Jezierska, Joanna Wiśniewska, Iwona Łakomska. Synthesis, structure and biological evaluation of ruthenium(III) complexes of triazolopyrimidines with anticancer properties. Journal of Biological Inorganic Chemistry 25, 109-124, 2020. (IF=3,358; MNiSW=70; Q2)
  10. Michalina Ehlert, Aleksandra Radtke, Tomasz Jędrzejewski , Katarzyna Roszek, Michał Bartmański, Piotr Piszczek. In vitro studies on nanoporous, nanotubular and nanosponge-like titania coatings, with the use of adipose-derived stem cells. Materials 13(7), 1574, 2020. (IF=3,623; MNiSW=140 pkt.; Q2)
  11. Marzena Fandzloch, Adam Wiktor Augustyniak, Liliana Dobrzanska, Tomasz Jędrzejewski, Jerzy Sitkowski, Magdalena Wypij, Patrycja Golinska. First dinuclear rhodium (II) complexes with triazolopyrimidines and the prospect of their potential biological use. Journal of Inorganic Biochemistry 210, 111072, 2020. (IF=4,155; MNiSW=70 pkt.; Q1)
  12. Magdalena Wypij, Tomasz Jędrzejewski, Maciej Ostrowski, Joanna Trzcińska, Mahendra Rai, Patrycja Golińska. Biogenic Silver Nanaparticles: Assessment of Their Cytotoxicity, Genotoxicity and Study of Capping Proteins. Molecules 25(13), 3022, 2020. (IF=4,411; MNiSW=100 pkt.; Q2)


  1. Irena Ponikowska, Henryk Mikołaj Kozłowski, Przemysław Adamczyk, Sylwia Wrotek. Hipertermoterapia ogólnoustrojowa – zastosowanie w medycynie. Acta Balneol, TOM LXI, Nr 4(158), 269-273, 2019.
  2. Aleksandra Radtke, Michalina Ehlert, Tomasz Jędrzejewski, Beata Sadowska, Marzena Więckowska-Szakiel, Jani Holopainen, Mikko Ritala, Markku Leskelä, Michał Bartmański, Marek Szkodo, Piotr Piszczek. Titania nanotubes/hydroxyapatite nanocomposites produced with the use of the atomic layer deposition technique: estimation of bioactivity and nanomechanical properties. Nanomaterials 9(1), 123, 2019.
  3. Aleksandra Radtke, Michalina Ehlert, Tomasz Jędrzejewski, Michał Bartmański. The Morphology, Structure, Mechanical Properties and Biocompatibility of Nanotubular Titania Coatings before and after Autoclaving Process. Journal of Clinical Medicine 8(2), 272, 2019.
  4. Aleksandra Radtke, Marlena Grodzicka, Michalina Ehlert, Tomasz Jędrzejewski, Magdalena Wypij, Patrycja Golińska. “To be Microbiocidal and Not to be Cytotoxic at the Same Time…” – Silver nanoparticles and Their Main Role on the Surface of Titanium Alloy Implants. Journal of Clinical Medicine 8(3), 334, 2019.
  5. Tomasz Jędrzejewski, Jakub Piotrowski, Małgorzata Pawlikowska, Sylwia Wrotek, Wieslaw Kozak. Extract from Coriolus versicolor fungus partially prevents endotoxin tolerance development by maintaining febrile response and increasing IL-6 generation. Journal of Thermal Biology 83, 69-79, 2019.
  6. Jakub Piotrowski, Tomasz Jędrzejewski, Małgorzata Pawlikowska, Sylwia Wrotek Wieslaw Kozak. High mobility group box 1 protein released in the course of aseptic necrosis of tissues sensitizes rats to pyrogenic effects of lipopolysaccharide. Journal of Thermal Biology 84, 36-44, 2019.
  7. Michalina Ehlert, Katarzyna Roszek, Tomasz Jędrzejewski, Michał Bartmański, Aleksandra Radtke. Titania Nanofiber Scaffolds with Enhanced Biointegration Activity – Preliminary In Vitro Studies. International Journal of Molecular Sciences 20 (22), 5642, 2019.
  8. Alicja Malina, Małgorzata Głogiewicz, Jakub Piotrowski. Supportive Social Interactions in Infertility Treatment Decrease Cortisol Levels: Experimental Study Report. Frontiers in Psychology 10, 2779, 2019.


  1. Aleksandra Radtke, Monika Bal, Tomasz Jędrzejewski. Novel titania nanocoatings produced by the anodic oxidation with the use of the cyclically changing potential; their photocatalytic activity and biocompatibility. Nanomaterials 8(9), 712, 2018.
  2. Wieslaw Kozak, Tomasz Jedrzejewski, Malgorzata Pawlikowska, Jakub Piotrowski, Sylwia Wrotek. Towards antitumor immunity and acute infectious fever: gamma/delta T cells hypothesis. Quarterly Review of Biology 93(3), 187-205, 2018.
  3. Sylwia Wrotek, Łukasz Brycht, Weronika Wrotek, Wiesław Kozak. Fever as a factor contributing to long-term survival in a patient with metastatic melanoma: a case report. Complementary Therapies in Medicine 38, 7-10, 2018.
  4. Joanna Wyszkowska, Tomasz Jędrzejewski, Jakub Piotrowski, Anna Wojciechowska, Maria Stankiewicz, Wieslaw Kozak. Evaluation of the influence of in vivo exposure to extremely low-frequency magnetic fields on the plasma levels of pro-inflammatory cytokines in rats. International Journal of Radiation Biology 94(10), 909-917, 2018.


  1. Piotr Piszczek, Żaneta Lewandowska, Aleksandra Radtke, Tomasz Jędrzejewski, Wiesław Kozak, Beata Sadowska, Magdalena Szubka, Ewa Talik, Fabrizio Fiori. Biocompatibility of Titania Nanotube Coatings Enriched with Silver Nanograins by Chemical Vapor Deposition. Nanomaterials 7(9), 274, 2017.
  2. Jakub Piotrowski, Tomasz Jędrzejewski, Małgorzata Pawlikowska, Agata Joanna Pacuła, Jacek Ścianowski, Wiesław Kozak. The weakening effect of soluble epoxide hydrolase inhibitor AUDA on febrile response to lipopolysaccharide and turpentine in rat. Journal of Physiology and Biochemistry 73: 551-560, 2017.
  3. Aleksandra Radtke, Tomasz Jędrzejewski, Wiesław Kozak, Beata Sadowska, Marzena Więckowska-Szakiel, Ewa Talik, Maarit Mäkelä, Markku Leskelä, Piotr Piszczek. Optimization of the Silver Nanoparticles PEALD Process on the Surface of 1-D Titania Coatings. Nanomaterials 7(7), 193, 2017.
  4. Aleksandra Radtke, Adrian Topolski, Tomasz Jędrzejewski, Wiesław Kozak, Beata Sadowska, Marzena Więckowska-Szakiel, Magdalena Szubka, Ewa Talik, Lars Pleth Nielsen, Piotr Piszczek. The bioactivity and photocatalytic properties of titania nanotube coatings produced with the use of the low potential anodization of Ti6Al4V alloy surface. Nanomaterials 7(8), 197, 2017.
  5. Jakub Piotrowski, Tomasz Jędrzejewski, Małgorzata Pawlikowska, Wiesław Kozak. Znaczenie gorączki i endogennej antypirezy. Perspektywa wykorzystania inhibitorów rozpuszczalnej hydrolazy epoksydowej w farmakologii przeciwgorączkowej. Kosmos 66 (2): 327-335, 2017.
  6. Aleksandra Radtke, Adrian Topolski, Tomasz Jędrzejewski, Wiesław Kozak, Beata Sadowska, Marzena Więckowska-Szakiel, Piotr Piszczek. Bioactivity Studies on Titania Coatings and the Estimation of Their Usefulness in the Modification of Implants Surface. Nanomaterials 7(4), 90, 2017.
  7. Sylwia Wrotek, Krzysztof Domagalski, Tomasz Jędrzejewski, Eliza Dec, Wiesław Kozak. Buthionine sulfoximine, a glutathione depletor, attenuates endotoxic fever and reduces IL-1b and IL-6 level in rats. Cytokine 90: 31-37, 2017.


  1. Małgorzata Pawlikowska, Tomasz Jedrzejewski, Jakub Piotrowski, Wiesław Kozak. Fever-range hyperthermia inhibits cells immune response to protein-bound polysaccharides derived from Coriolus versicolor extract. Molecular Immunology 80: 50-57, 2016.
  2. Tomasz Jędrzejewski, Małgorzata Pawlikowska, Jakub Piotrowski, Wiesław Kozak. Protein-bound polysaccharides from Coriolus versicolor attenuate LPS-induced synthesis of pro-inflammatory cytokines and stimulate PBMCs proliferation. Immunology Letters 178: 140-147, 2016.
  3. Sylwia Wrotek, Tomasz Jędrzejewski, Jakub Piotrowski, Wiesław Kozak. N-acetyl-L-cysteine exacerbates generation of IL-10 in cells stimulated with endotoxin in vitro and produces antipyresis via IL-10 dependent pathway in vivo. Immunology Letters 177: 1-5, 2016.
  4. Małgorzata Kowalczewska, Jakub Piotrowski, Tomasz Jędrzejewski, Wiesław Kozak. Polysaccharide peptides from Coriolus versicolor exert differential immunomodulatory effects on blood lymphocytes and breast cancer cell line MCF-7 in vitro. Immunology Letters 174: 37-44, 2016.
  5. Sylwia Wrotek, Tomasz Jędrzejewski, Anna Nowakowska, Wiesław Kozak. LPS alters pattern of sickness behavior but does not affect glutathione level in aged male rats. Biogerontology 17: 715-723, 2016.


  1. Sylwia Wrotek, Tomasz Jędrzejewski, Anna Nowakowska, Wiesław Kozak. Glutathione deficiency attenuates endotoxic fever in rats. International Journal of Hyperthermia 31(7): 793-799, 2015.
  2. Jedrzejewski Tomasz, Piotrowski Jakub, Kowalczewska Malgorzata, Wrotek Sylwia, Kozak Wieslaw. Polysaccharide peptide from Coriolus versicolor induces interleukin 6-related extension of endotoxin fever in rats. International Journal of Hyperthermia 31(6): 626-634, 2015
  3. Żaneta Lewandowska, Piotr Piszczek, Aleksandra Radtke, Tomasz Jędrzejewski, Wiesław Kozak, Beata Sadowska. The evaluation of the impact of titania nanotube covers morphology and crystal phase on their biological properties. Journal of Materials Science: Materials in Medicine 26 (163): 1-12, 2015
  4. T.W. Rosochowicz, S. Wrotek, W. Kozak. Axonal regeneration inhibitors: emerging therapeutic options. Acta Neurologica Belgica, 2015.

2014 i wcześniej

  1. Kozak, W. Regulated decreases of body temperature. In Fever. Basic Mechanisms and Management. 2nd edition. P.A. Mackowiak, editor. Lippincott-Raven Publ. pp.467-478, 1997.
  2. Kozak, W., V. Poli, D. Soszynski, C.A. Conn, L.R. Leon, and M.J. Kluger. Sickness behavior in mice deficient in interleukin-6 during turpentine abscess and influenza pneumonitis. Am. J. Physiol. 272:R621-R630, 1997.
  3. Leon, L.R., W. Kozak, J. Peschon, M. Glaccum, and M.J. Kluger. Altered acute phase response to inflammation in IL-1 and TNF receptor knockout mice. Ann. N.Y. Acad. Sci. 813:244-254, 1997.
  4. Kozak, W., D. Soszynski, C.A. Conn, K. Rudolph, L.R. Leon, and M.J. Kluger. Soluble TNF-a receptor prevents decrease of body temperature in mice injected with indomethacin and lipopolysaccharide. Ann. N.Y. Acad. Sci. 813:264-271, 1997.
  5. Kozak, W., D. Soszynski, K. Rudolph, C.A. Conn, and M.J. Kluger. Dietary n-3 fatty acids differentially affect sickness behavior in mice during local and systemic inflammation. Am. J. Physiol. 272:R1298-R1307, 1997.
  6. Kozak, W., J.J. Klir, C.A. Conn, and M.J. Kluger. Attenuation of lipopolysaccharide fever in rats by protein kinase C inhibitors. Am. J. Physiol. 273:R873-R879, 1997.
  7. Kluger, M.J., W. Kozak, L.R. Leon, and C.A. Conn. The use of knockout mice to understand the role of cytokines in fever. Clin. Exp. Pharmacol. Physiol. 25:141-144, 1998.
  8. Kluger, M.J., W. Kozak, L.R. Leon, D. Soszynski, and C.A. Conn. Fever and Antipyresis. In: Brain Function in Hot Environment. Sharma H.S., and Westman J., ed. Progress in Brain Research Vol. 115, pp. 465-475. Elsevier Science Publisher, Amsterdam, 1998.
  9. Sopori, M.L., W. Kozak, S.M. Savage, Y. Geng, and M.J. Kluger. Nicotine-induced modulation of T cell function: implications for inflammation and infection. In: Advences in Experimental Medicine and Biology, Vol. 402: Drugs of Abuse, Immunomodulation, and AIDS. Editors: H. Friedman, T.K Eisenstein, J. Madden, and B.M. Sharp. Plenum Press, New York, 1998, pp. 279-289.
  10. Sopori, M.L., W. Kozak. Immunomodulatory effects of cigarette smoke. J. Neuroimmun. 83:148-156, 1998.
  11. Kluger, M.J., W. Kozak, C.A. Conn, L.R. Leon, and D. Soszynski. Role of fever in disease. Ann. N.Y. Acad. Sci. 856:224-233, 1998.
  12. Kozak, W., I. Archuleta, K.P. Mayfield, A. Kozak, K. Rudolph, and M.J. Kluger. Inhibitors of alternative pathways of arachidonate metabolism differentially affect fever in mice. Am. J. Physiol. 275:R1031-R1040, 1998.
  13. Kozak, W., M.J. Kluger, D. Soszynski, C.A. Conn, K. Rudolph, L.R. Leon, and H. Zheng. IL-6 and IL-1b in fever: Studies using cytokine-deficient (knockout) mice. Ann. N.Y. Acad. Sci. 856:33-47, 1998.
  14. Leon, L.R., W. Kozak, K. Rudolph, and M.J. Kluger. An antipyretic role for interleukin-10 in LPS fever in mice. Am. J. Physiol. 276:R81-R89, 1999.
  15. Kozak, W., K.P. Mayfield, A. Kozak, M.J. Kluger. Proadifen (SKF-525A), an inhibitor of cytochrome P-450, augments LPS-induced fever and exacerbates prostaglandin-E2 levels in the rat. J. Thermal Biol. 25:45-50, 2000.
  16. Mayfield, K.P., D. Soszynski, W. Kozak, A. Kozak, K. Rudolph, and M.J. Kluger. b-Adrenergic receptor subtype effects on stress fever and thermoregulation. Neuroimmunomodulation 6:305-317, 1999.
  17. Szewczenko-Pawlikowski, M., W. Kozak. Accumulation of unsaturated lipids in monocytes during early phase pyrogen tolerance. Biochem. Biophys. Acta 1484:183-194, 2000.
  18. Kozak, W., M.J. Kluger, A. Kozak, M. Wachulec, and K. Dokładny. Role of cytochrome P-450 in endogenous antipyresis. Am. J. Physiol. 279:R455-R460, 2000.
  19. Kozak, W., M.J. Kluger, J. Tesfaigzi, M. Wachulec, A. Kozak, and K. Dokładny. Molecular mechanism of fever and antipyresis. Ann. N.Y. Acad. Sci. 917:121-134, 2000.
  20. Kluger, M.J., W. Kozak, and K.P. Mayfield. Fever and immunity. In Psychoneuroimmunology, 3rd edition, edited by R. Ader, D. Felten and N. Cohen. Academic Press, San Diego. Vol. 1, pp. 687-701, 2001.
  21. Foster JE, Gott K, Schuyler MR, Kozak W, Tesfaigzi Y. LPS-induced neutrophilic inflammation and Bcl-2 expression in metaplastic mucous cells. Am J Physiol Lung Cell Mol Physiol. 2003 Aug;285(2):L405-14. Epub 2003 Apr 18.
  22. Kozak W, Kozak A. Genetic Models in Applied Physiology. Differential role of nitric oxide synthase isoforms in fever of different etiologies: studies using Nos gene-deficient mice. J Appl Physiol. 2003 Jun;94(6):2534-44. Epub 2003 Jan 31.
  23. Kozak W, Aronoff DM, Boutaud O, Kozak A. 11,12-epoxyeicosatrienoic acid attenuates synthesis of prostaglandin E2 in rat monocytes stimulated with lipopolysaccharide. Exp Biol Med (Maywood). 2003 Jul;228(7):786-94.
  24. Kozak W., V. Fraifeld. Non-prostaglandin eicosanoids in fever and anapyrexia. Frontiers in Bioscience 9:3339-3355, 2004.
  25. Wrotek S., Dąbrowska G., Tretyn A. Czy istnieje roślinny homolog zwierzęcego peptydu natriuretycznego? Postępy Biologii Komórki 32:449-462, 2005
  26. Kozak, W., Wrotek, S., Kozak, A., Pyrogenicity of CpG-DNA in mice: Role of interleukin-6, cyclooxygenases, and nuclear-factor-kappa-B. Am J Physiol Regul Integr Comp Physiol. 290(4):R871-80, 2006
  27. Wrotek, S., Dąbrowska, G., Tyburski, J., Tretyn, A., There is no proof for the existence of atrial natriuretic peptide (ANP) homologue in a plant Pharbitis nil, Medical and Biological Sciences, 20(4): 181-186, 2006
  28. Wrotek S., Rosochowicz T., Nowakowska A., Kozak W. Thermal and motor behavior in experimental autoimmune encephalitis in Lewis rats. Autoimmunity 47 (5): 334-340, 2014
  29. Walentynowicz, K., Szefer, M., Wojtal, B., Terlecki, P., Wrotek, S., Kozak, W. Role of prostaglandins in heme-induced fever. J Physiol Pharm 57: 73-82, 2006
  30. Kozak, W., Wrotek, S., Walentynowicz, K., Hypoxia-induced sickness behaviour. J Physiol Pharm 57: 35-50, 2006
  31. Kozak, W., Wrotek, S., Walentynowicz, K., Waszak, P., Fever and symptoms of sickness are present in mice lacking functional B and T lyphocytes, Acta Biologica Cracoviensis 48: 9-20, 2006
  32. Kozak W, Kozak A, Johnson MH, Elewa HF, Fagan SC: Vascular protection with candesartan after experimental acute stroke in hypertensive rats: A dose- response study. J. Pharmacol. Exp. Therap. 326:773-782, 2008.
  33. Wrotek S., Kamecki K., Kwiatkowski S., Kozak W. Cancer patients report a history of fewer fevers during infections than healthy controls. Journal of Pre-Clinical and Clinical Research, 3: 031-035, 2009.
  34. Kozak W. Geneza gorączki. Biologiczne mechanizmy i praktyka medyczna. Wydawnictwo Naukowe UMK, 2009.
  35. Kowalczewska M., Wrotek. S., Jedrzejewski T., Kozak W. Cancer cachexia: mediating factors and the effect of eicosapentaenoic acid dieting. Journal of Pre-Clinical and Clinical Research 4 (2): 108-111, 2010.
  36. Wrotek S., Jedrzejewski T., Potera-Kram E., Kozak W. Antipyretic activity of N-Acetylcysteine. Journal of Physiology and Pharmacology, 62 (6): 669-675, 2011.
  37. Żbikowska E., Wrotek S., Cichy A., Kozak W. Thermal preferences of wintering snails Planorbarius corneus (L.) exposed to lipopolysaccharide and zymosan. Journal of Invertebrate Pathology, doi: 10.1016/j.jip.2012.08.011, 2012.
  38. Jedrzejewski T., Wrotek S., Piotrowski J., Kozak W. Silver nanoparticles augment releasing of pyrogenic factors by blood cells stimulated with LPS. Central European Journal of Biology 9 (11): 1058-1067, 2014.
  39. Jedrzejewski T., Piotrowski J., Wrotek S., Kozak W. Polysaccharide peptide induces a tumor necrosis factor-?-dependent drop of body temperature in rats. Journal of Thermal Biology 44: 1-4, 2014.
  40. Piotrowski J., Jedrzejewski T., Kozak W. Heme oxygenase-1 induction by cobalt protoporphyrin enhances fever and inhibitis pyrogenic tolerance to lipopolysaccharide. Journal of Thermal Biology 45: 69-74, 2014.