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Wybrane publikacje pracowników Katedry


Czarnecka J, Kwiatkowski M, Wiśniewski M, Roszek K (2021) Protein corona hinders N-CQDs oxidative potential and favors their application as nanobiocatalytic system. Int J Mol Sci 22(15): 8136.

Wypij M, Jędrzejewski T, Trzcińska-Wencel J, Ostrowski M, Rai M, Golińska P (2021) Green synthesized silver nanoparticles: antibacterial and anticancer activities, biocompatibility, and analyses of surface-attached proteins. Front Microbiol 12: 632505.

Wujak M, Kozakiewicz A, Ciarkowska A, Loch JI, Barwiolek M, Sokolowska Z, Budny M, Wojtczak A (2021) Assessing the interactions of statins with human adenylate kinase isoenzyme 1: fluorescence and enzyme kinetic studies. Int J Mol Sci 22(11): 5541.

Wiśniewski M, Czarnecka J, Bolibok P, Świdziński M, Roszek K (2021) New insight into the fluorescence quenching of nitrogen-containing carbonaceous quantum dots – from surface chemistry to biomedical applications. Materials 14(9): 2454.

Dąbrowska GB, Garstecka Z, Olewnik-Kruszkowska E, Szczepańska G, Ostrowski M, Mierek-Adamska A (2021) Comparative study of structural changes of polylactide and poly(ethylene terephthalate) in the presence of Trichoderma viride. Int J Mol Sci 22(7): 3491.

Ciarkowska A, Ostrowski M, Kozakiewicz A (2021) Biochemical characterization of recombinant UDPG-dependent IAA glucosyltransferase from maize (Zea mays). Int J Mol Sci 22(7): 3355.

Zieba W, Czarnecka J, Rusak T, Zieba M, Terzyk AP (2021) Nitric-acid oxidized single-walled carbon nanohorns as a potential material for bio-applications – toxicity and hemocompatibility studies. Materials 14(6): 1419.

Galgaro BC, Beckenkamp LR, Nunnenkamp MVM, Korb VG, Naasani LIS, Roszek K, Wink MR (2021) The adenosinergic pathway in mesenchymal stem cell fate and functions. Medicinal Research Reviews 41(4): 2316-2349.

Bolibok P, Szymczak B, Roszek K, Terzyk AP, Wiśniewski M. A New Approach to Obtaining Nano-Sized Graphene Oxide for Biomedical Applications. Materials 14(6): 1327.

Bieniek A, Terzyk A, Wiśniewski M, Roszek K, Kowalczyk P, Sarkisov L, Keskin S, Kaneko K (2021) MOF materials as therapeutic agents, drug carriers, imaging agents and biosensors in cancer biomedicine: recent advances and perspectives. Progress in Materials Science 117: 100743.

Ehlert M, Radtke A, Roszek K, Jędrzejewski T, Piszczek P (2021) Assessment of titanate nanolayers in terms of their physicochemical and biological properties. Materials 14(4): 806.

Ostrowski M, Ciarkowska A (2021) Pea GH3 acyl acid amidosynthetase conjugates IAA to proteins in immature seeds of Pisum sativum L. : a new perspective on formation of high-molecular weight conjugates of auxin. J Plant Physiol 256: 153312


Nemecz D, Ostrowski M, Ravatin M, Saul F, Faure G (2020) Crystal structure of isoform CBd of the basic phospholipase A2 subunit of crotoxin: description of the structural framework of CB for interaction with protein targets. Molecules 25(22): 5290

Czarnecka J, Wiśniewski M, Forbot N, Bolibok P, Terzyk AP, Roszek K (2020) Cytotoxic or not? Disclosing the toxic nature of carbonaceous nanomaterials through nano-bio interactions. Materials 13(9): E2060.

Zięba M, Korczeniewski E, Zięba W, Bolibok P, Czarnecka J, Płońska-Brzezińska ME, Terzyk AP(2020) Electrophoretic deposition of spherical carbon nanoobjects—A comparison of different biocompatible surfaces, Medical Devices and Sensors, Volume 3, Issue 6, Article No. e10075, Pages 1-11

Ehlert M, Radtke A, Jędrzejewski T, Roszek K, Bartmański M, Piszczek P (2020) In Vitro Studies on Nanoporous, Nanotubular and Nanosponge-Like Titania Coatings, with the Use of Adipose-Derived Stem Cells. Materials 13(7): E1574.

Wypij M, Jędrzejewski T, Ostrowski M, Trzcińska J, Rai M, Golińska P (2020) Biogenic silver nanoparticles : assessment of their cytotoxicity, genotoxicity and study of capping proteins. Molecules 25(13): 1-19.

Forbot N, Bolibok P, Wiśniewski M, Roszek K (2020) Carbonaceous nanomaterials-mediated defense against oxidative stress. Mini-Reviews in Medicinal Chemistry, 2020, Vol. 20, 4, 294-307

Ostrowski M, Ciarkowska A, Dalka A, Wilmowicz E, Jakubowska A (2020) Biosynthesis pathway of indole-3-acetyl-myo-inositol during development of maize (Zea mays L.) seeds. J Plant Physiol 245: 153082


Ehlert M, Roszek K, Jędrzejewski T, Bartmański M, Radtke A. (2019) Titania nanofiber scaffolds with enhanced biointegration activity – preliminary in vitro Int J Mol Sci 20(22), pii: E5642.

Bieniek A, Wiśniewski M, Roszek K, Bolibok P, Terzyk AP, Ferrer P, da Silva I. (2019) New strategy of controlled, stepwise release from novel MBioF and its potential application for drug delivery systems. Adsorption 9(12): 1280-1284.

Roszek K, Wujak M. (2019) How to influence the mesenchymal stem cells fate? Emerging role of ecto-enzymes metabolizing nucleotides. Journal of Cellular Physiology 234 (1): 320-334.

Cieślak M, Roszek K, Wujak M. (2019) Purinergic implication in amyotrophic lateral sclerosis – from pathological mechanisms to therapeutic perspectives. Purinergic Signal 15: 1-15.

Kućko A, Wilmowicz E, Ostrowski M (2019) Spatio-temporal IAA gradient is determined by interactions with ET and governs flower abscission. J Plant Physiol 236: 51-60


Wiśniewski M, Bieniek A, Roszek K, Czarnecka J, Bolibok P, Ferrer P, da Silva I, Terzyk AP (2018). Cystine-based MBioF for Maintaining the Antioxidant?Oxidant Balance in Airway Diseases. ACS Med. Chem. Lett. 8: 1280-1284

Ciarkowska A, Ostrowski M, Jakubowska A (2018). A serine carboxypeptidase-like acyltransferase catalyzes synthesis of indole-3-acetic (IAA) ester conjugate in rice (Oryza sativa). Plant Physiol Biochem 125: 126-135.

Ciarkowska A, Ostrowski M, Starzyńska E, Jakubowska A (2018). Plant SCPL acyltransferases: multiplicity of enzymes with various functions in secondary metabolism. Phytochem Rev; doi: 10.1007/s11101-018-9593-x [Epub ahead of print]

Wilmowicz E, Kućko A, Ostrowski M, Panek K (2018). INFLORESCENCE DEFICIENT IN ABSCISSION-like is an abscission associated and phytohormone-regulated gene in flower separation of Lupinus luteus. Plant Growth Regulation; doi: 10.1007/s10725-018-0375-7 [Epub ahead of print]

Wołczuk K, Ostrowski M, Ostrowska A, Napiórkowska T (2018). Structure of the alimentary tract in the Atlantic mudskipper Periophthalmus barbarus (Gobiidae: Oxudercinae): anatomical, histological and ultrastructural studies. Zoology; doi: 10.1016/j.zool.2018.04.002 [Epub ahead of print]

Jaouani K, Karmous I, Ostrowski M, El Ferjani E, Jakubowska A, Chaoui A (2018). Cadmium effects on embryo growth of pea seeds during germination: investigation of the mechanisms of interference of the heavy metal with protein mobilization-related factors. J Plant Physiol 226: 64-76.

Bajek A, Olkowska J, Walentowicz-Sadłecka M, Sadłecki P, Grabiec M, Porowińska D, Drewa T, Roszkowski K (2018). Human Adipose-Derived and Amniotic Fluid-Derived Stem Cells: A Preliminary In Vitro Study Comparing Myogenic Differentiation Capability. Med Sci Monit 24: 1733-1741.

Wypij M, Świecimska M, Czarnecka J, Dahm H, Rai M, Golińska P (2018). Antimicrobial and cytotoxic activity of silver nanoparticles synthesized from two haloalkaliphilic actinobacterial strains alone and in combination with antibiotics. J Appl Microbiol; doi: 10.1111/jam.13723 [Epub ahead of print]

Wypij M, Czarnecka J, Świecimska M, Dahm H, Rai M, Golińska P (2018). Synthesis, characterization and evaluation of antimicrobial and cytotoxic activities of biogenic silver nanoparticles synthesized from Streptomyces xinghaiensis OF1 strain. World J Microbiol Biotechnol 34: 1-13.

Bolibok P, Roszek K, Wiśniewski M (2018). Graphene Oxide-mediated protection from photodamage. J Phys Chem Lett 9: 3241-3244.

Hetmann A, Wujak M, Bolibok P, Zięba W, Wiśniewski M, Roszek K (2018). Novel biocatalytic systems for maintaining the nucleotide balance based on adenylate kinase immobilized on carbon nanostructures. Mater Sci Eng C, 88: 130-139.

Bolibok P, Roszek K, Wiśniewski M. (2018) Chemical and biochemical approach to make a perfect biocatalytic system on carbonaceous matrices. Methods in Enzymology 609: 221-245.


Bolibok P, Wiśniewski M, Roszek K, Terzyk AP. Controlling enzymatic activity by immobilization on graphene oxide. Sci. Nat. 2017, 104(3): 1-10

Zegarska B, Pietkun K, Zegarski W, Bolibok P, Wiśniewski M, Roszek K, Czarnecka J, Nowacki M. Air pollution, UV irradiation and skin carcinogenesis: what we know, where we stand and what is likely to happen in the future? Postępy Dermatol. Alergol. 2017, 34(1): 6-14

Cieślak M, Wojtczak A, Komoszyński M. Role of the purinergic signaling in epilepsy.  Pharmacol. Rep. 2017, 69(1): 130-138

Wujak M, Hetmann A, Porowińska D, Roszek K. Gene expression and activity profiling reveal a significant contribution of exo-phosphotransferases to the extracellular nucleotides metabolism in HUVEC endothelial cells. J. Cell. Biochem. 2017, 118(6): 1341-1348

Czarnecka J, Porowińska D, Bajek A, Hołysz M, Roszek K. Neurogenic differentiation of mesenchymal stem cells induces alterations in extracellular nucleotides metabolism. J. Cell. Biochem. 2017, (3): 478-486

Roszek K, Makowska N, Czarnecka J, Porowińska D, Dąbrowski M, Danielewska J, Nowak W. Canine adipose-derived stem cells : purinergic characterization and neurogenic potential for therapeutic applications. J. Cell. Biochem. 2017, 118(1): 58-65

Bajek A, Olkowska J, Walentowicz-Sadłecka M, Walentowicz P, Sadłecki P, Grabiec M, Bodnar M, Marszałek A, Dębski R, Porowińska D, Czarnecka J, Kaźmierski Ł, Drewa T. High quality independent from a donor : human amniotic fluid derived stem cells – a practical analysis based on 165 clinical cases. J. Cell. Biochem. 2017,118(1): 116-126

Wiśniewski M, Roszek K. Comment on “Elucidating the binding efficacy of ?-galactosidase on graphene by docking approach and its potential application in galacto-oligosaccharide production. Bioprocess Biosyst. Eng. 2017, 40(5): 797-798

Maj M, Bajek A, Nalejska E, Porowińska D, Kloskowski T, Gackowska L, Drewa T. Influence of mesenchymal stem cells conditioned media on proliferation of urinary tract cancer cell lines and their sensitivity to ciprofloxacin. J. Cell. Biochem. 2017, 118(6): 1361-1368


Ostrowski M, Porowińska D, Prochnicki T, Prevost MS, Raynal B , Baron B, Sauguet L, Corringer PJ, Faure G. Neurotoxic phospholipase A2 from rattlesnake as a new ligand and new regulator of prokaryotic receptor GLIC (proton-gated ion channel from G. violaceus). Toxicon. 2016, 116: 63-71

Bolibok P, Gembala J, Wujak M, Roszek K, Terzyk AP, Wiśniewski M. Immobilizacja enzymów na nośnikach sposobem na ukierunkowaną modyfikację właściwości biokatalizatorów. Enzyme immobilization on carriers as a way of directed modification of biocatalysator properties. Przem. Chem. 2016, 95(11): 2254-2258

Ostrowski M, Mierek-Adamska A, Porowińska D, Goc A, Jakubowska A. Cloning and biochemical characterization of indole-3-acetic acidamino acid synthetase PsGH3 from pea. Plant Physiol. Biochem. 2016, 107: 9-20,

Ciarkowska A, Ostrowski M, Jakubowska A. Abiotic stress and phytohormones affect enzymic activity of1-O-(indole-3-acetyl)-?-D-glucose: myo-inositol indoleacetyltransferase from rice (Oryza sativa). J. Plant Physiol. 2016, 205: 93-96

Ostrowski M, Ciarkowska A, Jakubowska A. The auxin conjugate indole-3-acetyl-aspartate affects responses to cadmium and salt stress in Pisum sativum L. J. Plant Physiol. 2016, 191: 63-72

Faure G, Bakouh N, Lourdel S, Odolczyk N, Premchandar A, Servel N, Hatton A, Ostrowski M, Xu H, Saul FA, Moquereau C, Bitam S, Pranke I, Planelles G, Teulon J, Herrmann H, Roldan A, Zielenkiewicz P, Dadlez M, Lukacs GL, Sermet-Gaudelus I, Ollero M, Corringer PJ, Edelman A. Rattlesnake phospholipase A2 increases CFTR-chloride channel current and corrects ?F508CFTR dysfunction: impact in cystic fibrosis. J. Mol. Biol. 2016, 428(14): 2898-2915

Wiśniewski M, Roszek K, Czarnecka J, Bolibok P. Węglowe kropki kwantowe jako potencjalne nośniki leków. Inż. Ochr. Śr. 2016, 19(2): 277-288

Faure G, Shelukhina IV, Porowińska D, Shulepko MA, Lyukmanova EN, Dolgikh DA, Spirova EN, Kasheverov IE, Utkin YN, Corringer PJ, Tsetlin VI. Interaction of three-finger proteins from snake venoms and from mammalian brain with the Cys-loop receptors and their models. Dokl. Biochem. Biophys. 2016, 468(1): 193-196

Faure G, Šeluhina IV, Porowińska D, Šulepko MA, L?kmanova EN, Dolgih DA, Spirova EN, Kaševerov IE, Utkin ?N, Corringer PJ, Cetlin VI. Vzaimodejstvie trehpetel’nyh belkov iz âda zmej i mozga mlekopita??ih s Cys-petel’nymi receptorami i ih modelâmi. Dokl. Akad. Nauk RAN. 2016, 468(2): 232-235

Hetmann A, Wujak M, Kowalczyk S. Protein transphosphorylation during the mutual interaction between phytochrome A and a nuclear isoform of nucleoside diphosphate kinase is regulated by red light. Biochemistry (Moscow). 2016, 81(10):1153-1162

Cieślak M, Czarnecka J, Roszek K. The roles of purinergic signaling in psychiatric disorders. Acta Biochim. Pol. 2016, 63(1): 1-9

Faure G, Porowińska D, Saul F. Crotoxin from Crotalus durissus terrificus and crotoxin-related proteins : structure and function relationship. Toxinology.  Toxins and drug discovery / ed.: P. Gopalakrishnakone. Dordrecht : Springer Science + Business Media, 2016, 1-19


Cieślak M, Czarnecka J, Roszek K, Komoszyński M. The role of purinergic signaling in the etiology of migraine and novel antimigraine treatment. Purinerg. Signal. 2015, 11(3): 307-316

Wujak M, Czarnecka J, Gorczycka M, Hetmann A. Kinazy adenylanowe człowieka: klasyfikacja, budowa oraz znaczenie w fizjologii i patologii. Human adenylate kinases: classification, structure, physiological and pathological importance. Postępy Hig. Med. Dośw. 2015, 69: 933-945

Ciarkowska A, Ostrowski M, Jakubowska A. Acylotransferazy uczestniczące w metabolizmie wtórnym roślin: klasyfikacja, struktura, mechanizm działania. Postępy Biochem. 2015, 61(1): 69-78

Ostrowski M, Kowalczyk S. Peptydy sygnałowe roślin: peptydy bogate w cysteinę. Postępy Biochem. 2015, 61(1): 79-92

Ostrowski M, Hetmann A, Jakubowska A. Indole-3-acetic acid UDP-glucosyltransferase from immature seeds of pea is involved in modification of glycoproteins. Phytochemistry. 2015, 117: 25-33

Nowacki M, Wiśniewski M, Werengowska-Ciećwierz KM, Roszek K, Czarnecka J, Łakomska I, Kloskowski T, Tyloch D, Dębski R, Pietkun K, Pokrywczyńska M, Grzanka D, Czajkowski R, Drewa G, Jundziłł A, Agyin JK, Habib SL, Terzyk AP, Drewa T. Nanovehicles as a novel target strategy for hyperthermic intraperitoneal chemotherapy : a multidisciplinary study of peritoneal carcinomatosis. Oncotarget. 2015, 6(26): 22776-22798

Roszek K, Czarnecka J. Is ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)-based therapy of central nervous system disorders possible? Mini-Rev. Med. Chem. 2015, 15: 5-20

Roszek K, Porowińska D, Bajek A, Hołysz M, Czarnecka J. Chondrogenic differentiation of human mesenchymal stem cells results in substantial changes of ecto-nucleotides metabolism. J. Cell. Biochem. 2015, 116(2): 2915-2923

Bajek A, Porowińska D, Kloskowski T, Brzoska E, Ciemerych MA, Drewa T. Cell therapy in Duchenne muscular dystrophy treatment : clinical trials overview. Crit. Rev. Eukar. Gene Expr. 2015, 25(1): 1-11

Werengowska-Ciećwierz KM., Wiśniewski M, Terzyk AP., Roszek K, Czarnecka J, Bolibok P, Rychlicki G. Conscious changes of carbon nanotubes cytotoxicity by manipulation with selected nanofactors. Appl. Biochem. Biotechnol. 2015, 176(3): 730-741